Senior Software Developer/Software Developer - Medical Genomics

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Salary range £31498 to £39729 pa plus excellent benefits. (Senior Software Developer).

Salary range £24589 to £30995 pa plus excellent benefits. (Software Developer).

We are looking for a Software Developer (or Senior Software Developer depending on experience) to work in Dr. Gosia Trynka's team at the Wellcome Trust Sanger Institute. Our group is an interactive mix of experimental and computational researchers. We combine immunology and genomic assays to understand the role of genetic variants in predisposing to development of immune diseases. We use computational and statistical methods to analyze large genomic datasets to better understand the causes of a wide range of human disorders, including celiac disease, rheumatoid arthritis, type 1 diabetes and inflammatory bowel disease.

This multifaceted role involves software development on open-source applications built for analysis of genomic data, scripting and analysis of big datasets, and design and implementation of the team's databases and software repositories. The successful candidate will be part of scientific analyses and discussions within the team, and will be expected to generate ideas for computational solutions to research problems. An interest in scientific research and a strong intellectual curiosity are necessities, whereas formal education in biology or genetics is helpful but not required.

Highly skilled developers are encouraged to apply regardless of prior job experience, as the focus is on coding and core computer science skills rather than on work experience. Recent graduates or current students in their final year are also encouraged to apply, although it is essential that any candidate has substantial development experience outside of coursework (e.g. active participation in open source projects or the pursuit of personal coding projects).

The successful applicant will have access to Sanger's world-class computational resources, including a 10,000+ core computational cluster and multiple petabytes of high-speed cluster filesystems (including over two petabytes of storage dedicated for human genetics use). Our work is also supported by an extremely knowledgeable and proactive systems group that maintains the core hardware and software infrastructure. The Sanger shares the Genome Campus with the European Bioinformatics Institute (EBI), and hosts a weekly talks on a variety of topics including informatics, given both by internal and external invited speakers. You would also have the opportunity to occasionally attend courses and/or conferences in order to keep up to date with new practices relevant to our work, both locally and potentially internationally.

Essential Skills

* BSc/BA in a computational or quantitative science discipline

* Strong background in computer programming, with experience in both large scale project development and smaller scripting tasks (e.g. via awk/perl/python)

* Knowledge of core development concepts (e.g. object oriented design, version control)

* Experience in UNIX computing environments

* Capacity for self-organization, timeline estimation, and teamwork

Ideal Skills

* MSc/MPhil/PhD in a computational or quantitative science discipline

* Knowledge of computer science concepts (e.g. machine learning, hidden markov models)

* Experience using high performance compute farms

* Interest or experience in human disease genetics or medical genomics

* Experience with large scale (terabytes or more) data processing

Other information

The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited's 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society.

To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.

Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

The closing date for applications is 20th January 2017. Please submit a cover letter and CV with your application.